Keto Last Card :We don’t get beta hydroxybutyrate, acetone, or acetoacetate (ketones) from the diet. The liver synthesises them only under duress; as a last measure in conditions of severe glucose deprivation like starvation. For the liver to be convinced that ketones are the order of the day, several conditions must be met.
At this point it is important to mention that it is not actually a question of being ‘in’ or ‘out’ of ketosis; we don’t either totally run on ketones, or not. It is a gradual and careful transition so that the brain is constantly and evenly fuelled… ideally. Ketones SHOULD be produced in small amounts from blood glucose levels of about 60mg/dl. We consider ourselves in ketosis when there are greater concentrations of ketones than glucose in the blood.
The reality is that most people – especially weight trainers – have had a regular intake of glucose for a good couple of decades, at least. The liver is perfectly capable of producing ketones but the highly efficient gluconeogenic pathways are able to maintain low-normal blood glucose above the ketogenic threshold.
Couple this with the fact that many people are at least partially insulin resistant and have elevated fasting insulin (upper end of the normal range, anyway). The small amount of blood glucose from gluconeogenesis induces sufficient insulin release to blunt glucagon output and the production of ketones.
Sudden glucose deprivation will have the consequence, initially, of lethargy, hunger, weakness etc in most people – until ketosis is achieved. And Ketosis will not be reached until the liver is forced to quit with gluconeogenesis and start producing ketones. As long as dietary protein is sufficient then the liver will continue to produce glucose and not ketones. That’s why no carb, high protein diets are NOT ketogenic.
Basically, when we are in ketosis our body is using fat (ketones) to fuel everything. As such, we aren’t breaking down muscle to provide glucose. That is, muscle is being spared because it has nothing to offer; fat is all the body needs (well, to a large extent). For the dieter this means substantially less muscle loss than what is achievable on any other diet. Make sense?
As a bonus, ketones yield only 7 calories per gram. This is higher than the equal mass of glucose but substantially less (22%, in fact) than the 9 calorie gram of fat from whence it came. We like metabolic inefficiencies like this. They mean we can eat more but the body doesn’t get the calories.
Even cooler is that ketones cannot be turned back into fatty acids; the body excretes any excess in the urine! Speaking of which, there will be quite a bit of urine; the drop in muscle glycogen, low Insulin and low aldosterone all equate to massive excretion of intra and extracellular fluid. For us that means hard, defined muscularity and quick, visible results. https://goldencondor.org/keto-last-card